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Folic acid dietary supplements are really helpful to scale back the danger of mind and spinal-wire abnormalities (called neural tube defects) that can happen in the first months of being pregnant. In: Coates PM, Betz JM, Blackman MR, et al., eds.: Encyclopedia of Dietary Dietary supplements. For example, calcium and vitamin D are necessary for holding bones robust and decreasing bone loss; folic acid decreases the chance of certain birth defects; and omega-3 fatty acids from fish oils might help some folks with coronary heart disease. The first indication is that creatine is a dietary complement that is broadly used. They should be used to compliment nutritious diet and good habits and not to compensate for poor consuming and a shabby way of life. Companies wishing to market a substance not included in the permitted checklist need to submit an software to the European Commission” ( 31 ). The number of supplements regulated under this technique just isn't reported because solely principal ingredients and their amount are regulated.